BioTek: Stem Cell Differentiation

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  Cell migration and invasion are live cell kinetic assays useful in oncology research. The principle difference between migration and invasion is that migration refers to normal cell movement; whereas invasion describes cells actively invading surrounding tissue. It can do this under the influence of a chemoattractant gradient and secretion of proteases. There are numerous methods for performing these assays including scratch assays performed on a monolayer of cells adhered to plasticware (microplates or culture inserts) or using 3D cell culture models.
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  G-protein coupled, seven-transmembrane (7-TM) receptors (GPCRs) represent large, diverse gene families found in fungi, plants and animals. The GPCR family of receptors is involved primarily with internalizing extracellular environmental signals via interaction with intracellular G-proteins. GPCR ligands and modulators range from peptide and non-peptide molecules to chemokines, nucleosides, growth factors and light.
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  Research into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long term importance of this research resides in the use of stem cells for regenerative therapies; for the short term, however these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents.
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  BioTek's Cytation 7 Cell Imaging Multi-Mode Reader Named ‘Best New Drug Discovery & Development Product’ at Scientists’ Choice Awards
  May 5, 2021 - BioTek Instruments is pleased to announce that the Cytation 7 Cell Imaging Multi-Mode Reader was awarded ‘Best New Drug Discovery & Development Product’ of 2020. The honor was voted upon by SelectScience members across the world and celebrated at the 2021 Scientists’ Choice Awards online awards ceremony. Read more
  
  BioTek Announces New Cytation C10 Confocal Imaging Reader
  February 2, 2021 - BioTek Instruments, a part of Agilent, is excited to unveil the Cytation C10, an advanced, automated Confocal Imaging Reader. This versatile and multi-functional automated system is ideal for research laboratories and core facilities looking to increase productivity while reaping high-quality qualitative and quantitative data to support cell-based research. Read more
  
  BioTek Receives Patent for Automated Media Exchange (AMX) Module for the MultiFlo FX Multi-Mode Dispenser
  January 28, 2021 - BioTek Instruments, an Agilent Technologies, Inc., company, announces that it was granted a patent by the United States Patent and Trademark Office for the Automated Media Exchange (AMX) module for the MultiFlo FX Multi-Mode Dispenser. In cell biology workflows, the automated MultiFlo FX with AMX module enables hands-free, gentle, and highly consistent media exchanges and washing in 96- and 384-well microplate formats without disturbing sensitive cells. This promotes viability and long-term differentiation in 3-dimensional (3D) cell culture models as well as effective maintenance of loosely adherent 2-dimensional (2D) cell cultures. Read more
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Home Applicazioni Stem Cell Research

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Stem Cell Differentiation

Research into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long-term importance of this research resides in the use of stem cells for regenerative therapies for the short term., However these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents. The process of differentiating stem cells into the somatic cell of choice is a long process requiring careful culturing. The process typically utilizes immunofluorescence techniques to determine progenitor cells and terminally differentiated somatic cells. The Agilent BioTek imaging products with liquid handling and Agilent BioTek BioSpa 8 automated CO₂ incubator have been designed to enable automated stem cell differentiation.

Application Notes:

Related Webinars:

Combining Automated Liquid Handling, Cellular Microscopy and Magnetic Bioprinting to Create Walk Away 3D Oncology, Stem Cell Differentiation, and Toxicity Procedures - On Demand

Related Products:

Agilent BioTek BioSpa Live Cell Imaging System
Agilent BioTek Cytation 7 Cell Imaging Multi-Mode Reader
Agilent BioTek Cytation 5 Cell Imaging Multi-Mode Reader
Agilent BioTek Cytation 1 Cell Imaging Multi-Mode Reader

Learn more about Stem Cell Research applications - search our application notes and technical documentation in resources.

For Research Use Only. Not for use in diagnostic procedures.

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